HRMS + ICP-MS
Cadmium (Cd)
Overview
A potent nephrotoxin and carcinogen. Cadmium has a biological half-life of 10–30 years in the kidney, making intracellular PBMC measurement a valuable long-term exposure indicator.
Primary Sources
Cigarette smoke, contaminated food (rice, leafy vegetables), industrial processes, phosphate fertilizers.
Health Effects
Renal tubular dysfunction, osteoporosis (itai-itai disease), lung damage, classified as a Group 1 human carcinogen.
Detection Method
This toxin is detected and quantified using HRMS + ICP-MS analysis of isolated PBMCs. The intracellular accumulation of this compound in lymphocytes and monocytes provides a more accurate reflection of chronic systemic burden than conventional serum or urine testing.