HRMS + ICP-MS
Arsenic (As)
Also known as: Inorganic arsenic · Arsenite · Arsenate
Overview
A ubiquitous environmental toxin and Group 1 carcinogen. Inorganic arsenic is the most toxic form and is readily taken up by immune cells.
Primary Sources
Contaminated groundwater, rice and rice products, treated wood (CCA), industrial smelting.
Health Effects
Skin lesions, peripheral neuropathy, cardiovascular disease, diabetes, multiple cancers (bladder, lung, skin).
Detection Method
This toxin is detected and quantified using HRMS + ICP-MS analysis of isolated PBMCs. The intracellular accumulation of this compound in lymphocytes and monocytes provides a more accurate reflection of chronic systemic burden than conventional serum or urine testing.